SCOPE initiates collaboration between the institutional research groups and pharmaceutical companies to create and transfer new innovations to the pharma sector. The institutional research group also provides research and development services to other institutes.
The Institute offers scientific services to research and business communities in the area of drug discovery and development. It currently employs over 25 scientists (faculty, scientific and professional staff) and carryout research projects for graduate and post graduate students…
Research area………
- Drug Design and Synthesis
- In vitro and In vivo Pharmacological Studies
- Toxicological Studies
- Herbal formulation and its standardization
- Drug Analysis and method development
- Formulation Development
- Troubleshooting
Instrumentation and other facilities…………..
SCOPE initiatives towards enriching its spectrum of pharmacy domain is seeing it moving towards associating itself with Pharma Burocrate’s through Drug Research and Development Centre laboratories who are equipped with cutting-edge technologies such as FTIR, HPLC, UV, Spray Dryer, Freeze Dryer, Cooling Centrifuge, , Gel Electrophoresis, Auto Analyzer, Fluorescent Microscopes, Rotatory Evaporator, USP Dissolution and Disintegration Apparatus, Brookfield Viscometer, Capsule Filling Machines, Coating Pan and Pilot Scale Tablet Manufacturing Unit. Computational Chemistry lab. equipped with Chem office and Approved Animal house having rats, mice, rabbits and guinea pigs.
DEPARTMENTS
Pharmaceutical Analysis & Quality Assurance
Analysis of drugs and pharmaceuticals forms the backbone of research and development in pharmaceutical industries. The department focuses on handling and training on the use modern analytical techniques such HPLC, FTIR, UV-Visible Spectroscopy, Flourimeter, Flame photometry, Karl Fischer app. etc. by the graduate and post graduate students and research scholars.
Special emphasis is laid on the implementation of good laboratory practices and analytical skills.
The department is actively involved in developing new analytical methods and their validation, characterization and quantitative estimation of API and other components in various dosage forms.
The Department has collaborated with leading pharmaceutical companies for projects in UV and HPLC based analytical method development and validation. This research in Pharmaceutical Analysis & Quality Assurance resulted into generation of valuable information that had been published in national and international journals and presentation have been made by Faculty and PG Students of the Department.
The Department has funding from various non-government organizations such as Rini Life Science Pvt. Ltd., Indore; Harshavardhan Pvt. Ltd. Lab., Indore; Vamso Biotech Pvt Ltd. Dehradun And Kevin Care Pvt. Ltd., Chennai.
Department of Pharmaceutical Chemistry
The department of pharmaceutical chemistry is one of the branches of the institute. It is equipped with state of the art facilities to undertake academics in Bachelor and Master of pharmacy course. Presently, the department has initiated research on Designing, molecular modeling, synthesis and biological activities. In the frontier area of medicinal chemistry research, focus will be laid on synthesis, purification, characterization and evaluation of biological activities both by in-vitro and in-vivo models.
To strengthen our academic and research potential, we introduce Computer aided drug design, Docking, QSAR and Molecular modeling based projects in master of pharmacy in pharmaceutical chemistry promoting identification and validation of novel target sites for designing and synthesizing new chemical entities having antidiabetic, antimalarial, antifungal, antitubercular, etc activities.
Research scholars, undergraduates and post-graduate students of the entire department are involved in UV and HPLC based analytical method development and its validation.
The Department has experienced and highly qualified faculty members who have been exposed to collaboration with institutions, Industries and having national and international publications.
The Department has funding from various governmental and non-government organizations such as MPCOST ; Rini Life Science Pvt. Ltd., Indore; Arjuna Natural Extracts Ltd., Kerala; Harshavardhan Lab., Indore; Vamso Biotech Pvt Ltd. Dehradun And Kevin Care Pvt. Ltd., Chennai.
Department of Pharmaceutics
The science and technology are associated with pharmacy has progressed enormously over the past few decades. Significant advances in understanding of diseases have necessitated the need to optimize the drug therapy. The pharmaceutical science includes emerging concepts, new theories and their practical applications in development and production of Pharmaceutical Dosage form referred to as Drug Delivery Systems.
Biopharmaceutics and Pharmacokinetics are the major branches of pharmaceutical sciences. Biopharmaceutics concerns with the relationship between the physical and chemical properties of a drug in a dosage form while Pharmacokinetics involves the application of mathematics and biochemistry in a physiologic and pharmacologic context.
The development of clinical pharmacokinetics is the culmination and logical outcome of advances in the area of pharmacokinetics, clinical pharmacology, toxicology and therapeutics.
The department works with the undergraduate and post graduate student in development of newer formulation. Formulations coming under NDDS, TDDS, nanoparticals, microspheres, dendrimers etc were formulated and query or troubleshooting involved during pilot plant scale-up and technology transfer in collaborated pharma industries were solved by the research scholars and the faculty members.
The Department was also involved with various pharma organizations such as Rini Life Science Pvt. Ltd., Indore;; Harshavardhan Lab., Indore And Kevin Care Pvt. Ltd., Chennai.
Department of Pharmacognosy
The department of Pharmacognosy is one of the important branches of the institute. It is equipped with all the facilities to undertake academics in Bachelor and Master of pharmacy course. The department has initiated research on extraction, isolation and purification and biological evaluation of phyto-chemical. In the area of research, department is involved in isolation of phyto-constituents, its purification, and evaluation of biological activities by animal models.
Our pharmacology department is equipped with all the required instruments and animals to carry out the research activities by graduates and Post graduates in Pharmacognosy students.
In the department of Pharmacognosy, herbal and poly herbal formulation were formulated and evaluated for their antidiabetic, antioxidant, antifungal, antitussive, hepatoprotective etc type of activities.
Research scholars, undergraduates and post-graduate students of department are involved in standardization of herbal formulation based on UV and HPLC.
The Department has experienced and highly qualified faculty members who have been exposed to collaboration with institutions, Industries and having national and international publications.
The Department has funding from various governmental and non-government organizations such as MPCOST ; Rini Life Science Pvt. Ltd., Indore; Arjuna Natural Extracts Ltd., Kerala; Harshavardhan Lab., Indore; Vamso Biotech Pvt Ltd. Dehradun And Kevin Care Pvt. Ltd., Chennai.
Department of Pharmacology
The department of pharmacology is equipped with all the required instruments and animals to carry out the research activities by the graduates and Post graduates in Pharmaceutical Chemistry and Pharmacognosy.
In the department of pharmacology, we learn about the action of various on the living tissues and then this knowledge is extended to the treatment of various diseases and thus forms the science of therapeutics.
The staff members of pharmacology Department are actively involved as research coordinators in executing projects related to diabetes mellitus, hyperlipidemia, cardiovascular system, psychopharmacology, drug delivery system and preclinical studies and toxicological evaluation.
A well equipped certified animal house is maintained by the Department in which herbal formulation, synthesized compounds were evaluated for their antidiabetic, antioxidant, antifungal, antitussive, hepatoprotective etc type of activities.
The Department of Pharmacology is equipped with equipments include: Polyrite, Non-invasive Blood Pressure Recorder, Auto analyzer, Computer attached Photo microscopy, Organ Bath, Operation Table, Haemocytometer, Haemoglobinometer, Analgesiometer, Convulsometer etc.
The Department has experienced and highly qualified faculty members who have been exposed to collaboration with institutions, Industries and having national and international publications.
The Department has collaboration with various organizations such as Rini Life Science Pvt. Ltd., Indore; Vamso Biotech Pvt Ltd. Dehradun And Kevin Care Pvt. Ltd., Chennai.
LABORATORIES
Pharmaceutics labs
The laboratories are equipped with new as well as conventional gadgets like Freeze Dryer, Spray Dryer, Tablet Machines, Capsule Filling Machines, Coating Pan, probe Sonicator, Brookfield Viscometer, USP Dissolution Rate Apparatus, Disintegration Apparatus, Friability Apparatus, Ovens, Shakers, Stirrers, Homogenizers,, etc. The working platforms have adequate water, gas and electricity supply. Each lab has attached storeroom, balance room and instrument room.
Pharmaceutical Chemistry Labs
Two laboratories for Pharmaceutical Chemistry experimentation are there in the Institute. Both the labs have all working amenities including the bio-safety hood and attached storeroom, balance room and instrument room having IR, HPLC, UV, Rotatory Evaporator, Gel Electrophoresis, Flame Photometer, Cooling Centrifuge, Karl Fischer etc.
Pharmacognosy Labs
Pharmacognosy Labs, equipped with required gadgets like Trinocular Microscope, Extractors, Column for Chromatography etc. Labs have a collection of around 200 crude drug samples and are substantiated with Medicinal Garden.
Pharmacology Labs
Pharmacology lab is fitted with conventional equipments like Organ Bath, Operation Table, Autoanalyzer, Haemocytometer, Haemoglobinometer, Analgesiometer, Convulsometer etc. An Animal house, which house rabbits, rats, guinea pigs etc. supports the lab.
Computer Center
A fully developed computer center with 25 interconnected terminals provides computational facilities to the students and researchers. The center is equipped with Internet connectivity and printing facilities and provides accessibility for 12 hours on working days.
LIST OF INSTRUMENT’S
| S.No. | Name of Instrument |
| 1 | 16 Station Tablet Machine |
| 2 | Actophotometer |
| 3 | Ampoule Sealing Machine |
| 4 | Analgesiometer |
| 5 | Analytical Balance |
| 6 | Analytical Balance |
| 7 | Aseptic Cabinet |
| 8 | Auto Analyzer |
| 9 | Auto Clave |
| 10 | Ball Mill |
| 11 | BOD Incubator |
| 12 | Brookfield viscometer |
| 13 | Bulk Density App. |
| 14 | Capsule Filling Machine |
| 15 | Cell Crusher |
| 16 | Centrifuge |
| 17 | Collapsible Tube Sealing Machine |
| 18 | Colony Counter |
| 19 | Colorimeter |
| 20 | Compressor Unit |
| 21 | Cooks Pole Climbing Apparatus |
| 22 | Cooling Centrifuge |
| 23 | Desiccators |
| 24 | Dhona balance |
| 25 | Digital Balance (Pocket) |
| 26 | Digital Conductivity Meter |
| 27 | Digital pH Meter |
| 28 | Digital Telethermometer |
| 29 | Disintegration Apparatus |
| 30 | Dissolution Test Apparatus |
| 31 | Distillation Apparatus |
| 32 | Double Distillation (Glass) |
| 33 | Double Distillation Unit |
| 34 | Double Organ Bath |
| 35 | Electroconvulsometer |
| 36 | Electronic Balance |
| 37 | Flame Photometer |
| 38 | Freeze Dryer |
| 39 | Friability App. |
| 40 | Fuming Hood |
| 41 | Hand Grinder |
| 42 | Hardness Tester |
| 43 | Heating Mantle |
| 44 | Histamine Chamber |
| 45 | Homogenizer |
| 46 | Hot Air Oven |
| 47 | Hot Plate |
| 48 | HPLC |
| 49 | Humidity chamber |
| 50 | Incinerator |
| 51 | Incubator |
| 52 | Ion Exchanger |
| 53 | IR Moisturizer Balance |
| 54 | IR Spectrophotometer |
| 55 | Isolated Organ Bath |
| 56 | KFR Apparatus |
| 57 | Kips Apparatus |
| 58 | Laminar Air Flow |
| 59 | Magnetic Stirrer |
| 60 | Melting Point Apparatus |
| 61 | Metabolic Cage |
| 62 | Micro-Centrifuge |
| 63 | Micropipette |
| 64 | Microscope |
| 65 | Microtome |
| 66 | Microwave Oven |
| 67 | Mono-ocular Microscope |
| 68 | Muffle Furnace |
| 69 | Ointment Filling Machine |
| 70 | Orbital Shaker |
| 71 | Oven 18″18″18″ |
| 72 | Paper Strip Horizontal Electrophoresis |
| 73 | Percolator |
| 74 | pH Meter |
| 75 | Plathismometer |
| 76 | Potentiometer |
| 77 | Polarimeter |
| 78 | Pressure Cooker |
| 79 | Programmable Environmental Test Chamber |
| 80 | Refractometer |
| 81 | Respirometer |
| 82 | Rota Rod |
| 83 | Rotating Drum |
| 84 | Rotatory Evaporate Fuming |
| 85 | Rotatory Vaccume Evaporator |
| 86 | Sieve |
| 87 | Sieve Shaker |
| 88 | Single Station Tablet Machine |
| 89 | Spray dryer |
| 90 | Suppository Mold |
| 91 | Trinocular Microscope |
| 92 | Ultra Violet Cabinet |
| 93 | UV Spectrophotometer 1700 |
| 94 | UV Spectrophotometer 1800 |
| 95 | Vaccume Pump |
| 96 | Vertical Shaker |
| 97 | Vertical Stirrer |
| 98 | Vortex Shaker |
INSTITUTE HAS DEVELOPED RESEARCH COLLABORATIONS WITH FOLLOWING INDUSTRIES
- Universal Corporation Ltd, Kenya
- Rini Life Sciences Pvt Ltd., Indore (M.P.)
- Harshavardhan Lab., Indore (M.P.)
- Vamso Biotech Pvt Ltd., Dehradun, Uttarakhand
- Cavinkare Pvt. Ltd., Chennai
- Council of Science & Technology Project (MPCOST).
- Arjuna Natural Extracts Ltd., Kerala.
- Marico Industries Pvt Ltd, Mumbai
- Promed Laboratories Pvt Ltd, Indore (M.P.)
- Pure Pharma Ltd, Indore (M.P.)
PRE-CLINICAL RESEARCH FACILITY
ANIMAL HOUSE
Animal House Facility
The institutional animal house facility is available to boost the teaching, training and research facilities and to meet the growing demand for high quality laboratory animals in emergent field of Experimental Pharmacology. Qualified veterinarians and technical personnel are always at hand to help carry out research and keep it in accordance with the standards established by the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA).
Animal Care
The institute has a well established Animal House, registered by Ministry of Environment and Forest, Government of India. It has facilities to house rats, mice and rabbits. All efforts are made to maintain the animals under controlled environmental conditions [Temperature (22-26°C), Relative Humidity (60 ± 10 %), and 12 hr alternate light and dark cycle] with 100 % fresh air exchange in animal rooms and uninterrupted power and water supply. The support staffs ensures that every part of animal care including feeding, watering, restraining, cage cleaning, record keeping and ordering of animals, feeds, bedding materials and equipment from outside sources are monitored. The animals themselves are isolated from human habitation and guarded from dust, smoke, noise, wild rodents, insects and birds-in fact anything that would disturb their habitat. A high degree of hygienic conditions around the animals are maintained as per the CPCSEA guidelines. The Institutional Animal Ethics Committee (IAEC) has been set up to monitor research proposals of students and faculty members involving animal study and give permissions for the same after thorough scrutiny.
Research Projects
Currently the IAEC has approved the following teaching and research programs:
- Toxicological studies
- Anti-inflammatory studies
- Diuretic studies
- Anti-diarrhoeal studies
- Hepatoprotective studies
- Anti-diabetic studies
- Immunomodulatory studies
- Ulcer protective studies
- Analgesic studies
- Anti tussive studies
- Antilithiatic studies
- Nephroprotective studies
- Hair growth studies
- Sexual dysfunction studies